どうにもならない
Adjective
1.
hopeless, futile, no use, beyond help, cannot be done
word usually written using kana alone
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どんなに努力しても、どうにもならないことがある。
No matter how much you try, there are some things that are beyond help.
締め切りが迫っているのに、パソコンが壊れてどうにもならない。
The deadline is approaching, but my computer broke, and there's nothing I can do.
過去の過ちを悔やんでも、今となってはどうにもならない。
Even if I regret past mistakes, there's nothing I can do about them now.
彼の病状は悪化の一途をたどり、もはやどうにもならない段階に達していた。
His medical condition continued to worsen, reaching a point where it was beyond help.
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